Completed and ongoing appraisals topics are listed below. Topics that were not accepted onto the appraisal work programme are also listed with the Topic Exploration Report (these do not include Evidence Appraisal Reports or guidance). Learn more about our appraisal process here.

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April 2024

Hearing aids to delay the onset or progression of dementia

Hearing aid provision to delay the onset or progression of dementia in people living with hearing loss
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April 2024

ELF test (Enhanced Liver Fibrosis)

The ELF test is a non-invasive blood test which combines three direct serum biomarkers of liver fibrosis. It is for…
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March 2024

Intensive Family Preservation Programmes (IFPP)

Intensive Family Preservation Programmes (IFPP) for families in crisis, where there is an imminent risk of out-of-home placement or children…
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March 2024

Video feedback interventions

Video feedback interventions to improve communication within family relationships and support children at risk
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March 2024

Kitelock 4%

Kitelock 4% in the prevention of central line catheter associated bloodstream infection and blood clots
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March 2024

Orthotic bracing for scoliosis

Orthotic bracing for the treatment of idiopathic scoliosis in children and young people
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March 2024

Slot-scanning, biplanar X-ray imaging (EOS imaging systems) for spine and lower limb conditions and orthopaedic surgery

Slot-scanning, biplanar X-ray imaging, such as EOS imaging systems, is a way of acquiring full body X-ray images using lower…
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March 2024

Community respiratory care services

Community based respiratory care services for people with chronic respiratory conditions
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March 2024

Liposuction for the treatment of chronic lymphoedema

Liposuction for the treatment of chronic lymphoedema
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March 2024

Computer-assisted thermography for breast cancer screening (Thermalytix)

Computer-assisted diagnostic tools for thermographic images to assist in diagnosis of malignant breast lesions.
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March 2024

Artificial intelligence for the diagnosis of chronic obstructive pulmonary disease at point-of-care

N-Tidal Diagnose (TidalSense) combines a high-resolution carbon dioxide sensor with an artificial intelligence platform to measure changes in lung function…
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January 2024

Digital wound management tools

Digital tools for the monitoring and management of wounds.
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January 2024

Low energy contact X-ray brachytherapy (CXB)

Low energy contact X-ray brachytherapy (CXB) for the treatment of early stage rectal cancer
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January 2024

Circulating tumour DNA tests for T790M mutations in non-small cell lung cancer

Circulating tumour DNA tests for T790M mutations in non-small cell lung cancer
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January 2024

Optical sensor devices for the detection of infiltration and extravasation of intravenous fluid

Optical sensor devices for the detection of infiltration and extravasation of intravenous fluid
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January 2024

Optical coherence tomography angiography for detection and diagnosis of vascular diseases of the eye

Optical coherence tomography angiography for detection and diagnosis of vascular diseases of the eye
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January 2024

Robot-assisted thoracic surgery

Robot-assisted thoracic surgery.
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January 2024

Advanced paramedic practitioners

Advanced paramedic practitioners for assessment and treatment of medical emergencies
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December 2023

Radiofrequency renal denervation

Renal denervation to treat people with resistant hypertension
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December 2023

Solution-focused assessment tools

Solution-focused assessment tools for improving the treatment of people with severe mental illness within secondary mental health services.
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December 2023

Percutaneous implantation of pulmonary artery pressure sensors

Percutaneous implantation of pulmonary artery pressure sensors for monitoring treatment of chronic heart failure.
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December 2023

Automated pH testing to verify placement of nasogastric feeding tubes

Automated pH testing to verify placement of nasogastric feeding tubes
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December 2023

Permanent implant brachytherapy devices for unresectable pancreatic cancer

Permanent implant brachytherapy devices for the treatment of locally advanced, unresectable pancreatic cancer
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December 2023

Clinical decision support software with integrated AI for the management of patients with incidental pulmonary nodules identified on chest CT scans (Optellum Virtual Node Clinic)

Clinical decision support software with integrated AI for the management of patients with incidental pulmonary nodules identified on chest CT…
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November 2023

Multi-grip upper limb prosthetics

Multi-grip myoelectric upper-limb prosthetics.
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September 2023

Myopia-control contact lenses and spectacles

Myopia-control contact lenses and spectacles to slow the progression of myopia in children and adolescents.
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September 2023

FloSeal in the treatment of epistaxis

FloSeal is a bioresorbable topical haemostatic agent which can be used in the treatment of epistaxis (nosebleeds) if first aid…
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September 2023

Artificial intelligence assisted tools for prostate cancer diagnosis using whole slide biopsy images

Artificial intelligence assisted tools for prostate cancer diagnosis using whole slide biopsy images
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September 2023

Digital cognitive assessment tools

Digital cognitive assessment tools to detect early-stage impairment caused by neurodegenerative disorders
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September 2023

Robot-assisted benign gynaecological surgery

Robot assisted benign gynaecological surgery
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September 2023

Pre-emptive pharmacogenetic (PGx) testing using a multiple gene panel to guide treatment and reduce adverse drug reactions

Pre-emptive pharmacogenetic (PGx) testing using a multiple gene panel to guide treatment decisions
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September 2023

Hyperspectral imaging for the detection of cutaneous melanoma

Hyperspectral imaging for the detection of cutaneous melanoma
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September 2023

Photobiomodulation therapy for dry age-related macular degeneration

Use of near infrared spectrum light to in the treatment of dry age-related macular degeneration
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September 2023

Digital tools for the remote assessment of visual acuity

Digital tools for the remote assessment of visual acuity
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June 2023

AI-assisted endoscopy for gastrointestinal cancer

Artificial Intelligence (AI)-assisted endoscopy in the detection of gastrointestinal cancer and pre-cancerous conditions.
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June 2023

IVUS (Intravascular ultrasound)

IVUS (Intravascular ultrasound) to guide percutaneous coronary intervention (PCI) for people with cardiovascular conditions
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June 2023

Urolon, a bioresorbable urethral bulking agent

Urolon, a bioresorbable urethral bulking agent for the treatment of stress urinary incontinence (SUI) among adult females.
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June 2023

MeMed BV testing to differentiate between bacterial and viral infections

MeMed BV testing to differentiate between acute bacterial and viral infection of the respiratory tract in the Hospital setting.
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June 2023

Smart peak flow meters

Smart peak flow meters for monitoring asthma.
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June 2023

MyDiabetesMyWay

MyDiabetesMyWay, a digital tool for diabetes management and education
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June 2023

Internet-based cognitive behavioural therapy in people with breast cancer

Internet-based cognitive behavioural therapy for mild-to-moderate depression or anxiety in people with breast cancer and survivors of breast cancer.
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June 2023

Spinal cord stimulation

Spinal cord stimulation for adults with chronic chemotherapy-induced peripheral neuropathy.
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June 2023

Wearable cardioverter defibrillators

Wearable cardioverter defibrillators for people at risk of cardiac death
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March 2023

Clinical decision tool with AI

A clinical decision support system with artificial intelligence (C the Signs) to facilitate early detection of cancer.
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March 2023

Digital companion robots

Digital companion robots to deliver remote care
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March 2023

Single pulse transcranial magnetic stimulation

Single pulse transcranial magnetic stimulation for the acute treatment or prevention of migraines.
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March 2023

Remote digital pose estimation

Remote digital pose estimation for orthopaedic injury or surgery
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March 2023

AI-assisted ultrasound

AI-assisted ultrasound for deep vein thrombosis
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March 2023

Photobiomodulation

Photobiomodulation for the prevention and treatment of oral mucositis associated with cancer treatment
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March 2023

Balloon dilation

Balloon dilation for chronic eustachian tube dysfunction
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March 2023

Cyanoacrylate glue occlusion

Cyanoacrylate glue occlusion for varicose veins.
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February 2023

Gracilis free-functioning muscle transfer

Gracilis free-functioning muscle transfer (FFMT) to restore upper limb function in brachial plexus injury
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February 2023

Ex-vivo lung perfusion

Ex-vivo lung perfusion for advanced pulmonary disease
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February 2023

Stereotactic radiosurgery

Stereotactic radiosurgery for trigeminal neuralgia
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February 2023

Electrical stimulation for people with chronic respiratory conditions, chronic heart failure and chronic kidney disease

Electrical stimulation to improve muscle strength and associated outcomes for people with chronic respiratory conditions, chronic heart failure and chronic…
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February 2023

Endoscopic balloon dilation

Endoscopic balloon dilation for subglottic or tracheal stenosis
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February 2023

Smartinhalers

Smartinhalers for people with asthma and other respiratory conditions
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February 2023

Personal SOS alarm wearables

Personal SOS alarm wearables for vulnerable and/or older people.
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February 2023

Retinal-based AI-enabled tool

Retinal-based AI-enabled tool to triage people at risk of cardiovascular disease
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February 2023

Digital psychological therapies

Digitally delivered psychological therapies for the treatment of depression
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February 2023

Electronic prescribing and medicines administration systems

Electronic prescribing and medicines administration systems for all secondary care inpatient and outpatient, including paediatric, settings.
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February 2023

Electronic prescribing and medicines administration systems

Electronic prescribing and medicines administration systems for all secondary care inpatient and outpatient, including paediatric, settings.
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February 2023

Ambulatory patch electrocardiography monitoring devices

Ambulatory patch electrocardiography monitoring devices used to detect cardiac arrhythmias
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January 2023

Passive monitoring technologies to support the independence of older adults living alone

Passive monitoring technologies to support the independence of older adults living alone by identifying changes from normal routines and the…
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January 2023

Stereotactic ablative body radiotherapy (SABR) for locally advanced exocrine pancreatic cancer

Stereotactic ablative body radiotherapy (SABR) for locally advanced exocrine pancreatic cancer.
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January 2023

Leadless cardiac pacemakers for bradyarrhythmias

Leadless cardiac pacemakers for bradyarrhythmias due to contraindications for conventional pacemakers
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January 2023

Co-ordinated treatment or management plans

Co-ordinated treatment or management plans for people with multi-morbidities
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January 2023

Clinical decision support software (CDSS) during emergency telephone triage

Clinical decision support software (CDSS) during emergency telephone triage for people identified as lower urgency who may be able to…
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December 2022

Virtual reality distraction therapy

Virtual reality therapy for the management of procedure-related pain.
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December 2022

Virtual wards

Virtual wards to deliver care in community settings
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November 2022

Continuous topical oxygen therapy

Continuous topical oxygen therapy to treat people with chronic non-healing and complex diabetic foot ulcers
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October 2022

Left atrial appendage occlusion in patients with atrial fibrillation

Left atrial appendage occlusion in patients with atrial fibrillation
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October 2022

Genetic testing (prostate cancer)

Genetic testing for prostate cancer care.
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October 2022

Autofluorescence imaging

Adjunctive autofluorescence imaging of oral mucosal abnormalities to identify malignancy or premalignancy, including, but not limited to, OralID
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October 2022

Geniculate artery embolisation

Geniculate artery embolisation to relieve long-term pain for adults with knee osteoarthritis
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September 2022

Digital platform to support older people at home

Digital platforms for older people to support independent living and self-management in the home.
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September 2022

Minuteful Kidney test

Minuteful Kidney test for people at risk of chronic kidney disease (CKD)
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September 2022

Processed or cadaveric nerve allografts (PNA)

Processed or cadaveric nerve allografts (PNA) to repair peripheral nerve discontinuities for people with peripheral nerve damage.
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September 2022

T2 Magnetic Resonance

T2 Magnetic Resonance to aid early diagnosis of sepsis
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September 2022

RayPilot

RayPilot, a novel real-time electromagnetic tracking device, used during radiotherapy to treat prostate cancer.
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September 2022

Real-time continuous glucose monitoring

Real-time continuous glucose monitoring of people with type 1 and 2 diabetes
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September 2022

Stereotactic ablative body radiotherapy (SABR)

Stereotactic ablative body radiotherapy (SABR) for oligoprogressive disease.
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September 2022

WavelinQ EndoAVF System

WavelinQ EndoAVF System for haemodialysis access for people with end stage renal failure.
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August 2022

Interventions at the transition from children’s to adults’ services

Interventions at the transition from children’s to adults’ services for people with long-term conditions
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August 2022

Osseointegration

Osseointegration for people with transfemoral amputations.
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July 2022

Outpatient laryngeal biopsy

Laryngeal biopsies in the outpatient setting in people with suspected head and neck dysplasia/cancer
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July 2022

Closed loop systems

Closed loop systems for the management of type 1 diabetes
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June 2022

Continuous respiratory rate monitor (RespiraSense)

A continuous respiratory rate monitor (RespiraSense) for people with multiple respiratory conditions.
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June 2022

Stereotactic ablative radiotherapy (SABR)

Stereotactic ablative radiotherapy (SABR) for the treatment of renal cell carcinoma
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June 2022

Powered lower limb exoskeletons

Powered lower limb exoskeletons to support the musculoskeletal system in adults and children with complex neurological impairments or spinal cord…
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June 2022

Interactive therapeutic devices/doll therapy (HUG)

Interactive therapeutic devices (doll therapy) in advanced dementia care
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June 2022

Remote monitoring with robotic-assist knee balancing system

Remote patient monitoring (RPM) with the robotic-assist knee balancing system for people undergoing total knee replacement arthroplasty
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June 2022

Prescription delivery application

Delivery tracking application for prescription deliveries
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June 2022

Hospital discharge services (Hospital to a Healthier Home)

Hospital discharge services to help make housing safe and accessible for older people
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June 2022

Bed monitoring and alarm systems in care homes

Bed monitoring systems to prevent falls and pressure injury in care homes.
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May 2022

Video laryngoscopes

Video laryngoscopes for use in pre-hospital care.
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May 2022

Electronic blood management systems

Electronic blood management systems for blood transfusions
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May 2022

Tumour profiling tests

Tumour profiling tests that guide treatment decisions for early breast cancer
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May 2022

DeltaScan Brain State Monitor

DeltaScan Brain State Monitor for the diagnosis of acute encephalopathy and/or delirium
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May 2022

Extreme HypoFractionated Radiotherapy (EHFRT)

Extreme HypoFractionated Radiotherapy (EHFRT) for localised prostate cancer
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