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Reports & Guidance

We publish three different types of report:

Topic Exploration Report (TER) – A TER is published once the initial evidence search on a topic has been carried out. The TER is presented  to the HTW Assessment Group who decide whether the topic should be accepted onto the HTW work programme.

Evidence Appraisal Report (EAR) – Once a topic is accepted onto the HTW work programme, the HTW researchers complete a rapid review of the available evidence on the topic, assess the evidence and draft an EAR. This is reviewed by the topic referrer, independent experts and the HTW Assessment Group before being finalised.

Guidance (GUI) – Guidance on whether the evidence supports adoption of a technology in Wales is produced by the HTW Appraisal Panel which appraises the evidence available in the EAR  alongside expert, patient and public input. The guidance summaries the key evidence and and any implications for the health and social care sectors in Wales.

Expert Review Documents: As part of our appraisal process, we invite experts on a particular topic to take part in an expert review of our draft Evidence Appraisal Report (EAR) on that topic. We ask reviewers to provide comment, either on specific issues/uncertainties that our research team need help clarifying, or the general content of the report and its robustness.  Expert review documents are available to view in the additional documents section of our topic pages.

A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Intranasal photodisinfection

Intranasal photodisinfection for the prevention of surgical site infections
Read moreabout Intranasal photodisinfection
A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Compression systems for lower limb ulcers and oedema

Multicomponent compression systems in a single bandage for lower limb ulcers and oedema
Read moreabout Compression systems for lower limb ulcers and oedema
A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Pharmacogenomic tests to predict clozapine response

Pharmacogenomic tests to predict clozapine response in treatment-resistant schizophrenia
Read moreabout Pharmacogenomic tests to predict clozapine response
A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Finger-worn sensors to diagnose and monitor sleep-disordered breathing

Finger-worn sensors to diagnose and monitor sleep-disordered breathing in children and adults
Read moreabout Finger-worn sensors to diagnose and monitor sleep-disordered breathing
A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Pharyngeal electrical stimulation

Pharyngeal electrical stimulation for swallowing difficulties resulting from neurogenic disorders in adults
Read moreabout Pharyngeal electrical stimulation
A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Clinical hyperthermia alongside radiotherapy and/or chemotherapy

Clinical hyperthermia alongside radiotherapy and/or chemotherapy for recurrent breast cancer
Read moreabout Clinical hyperthermia alongside radiotherapy and/or chemotherapy
A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Blood-based liquid biopsies

Blood-based liquid biopsies that analyse circulating stem cells and associated molecular markers for early cancer detection and triage
Read moreabout Blood-based liquid biopsies
A graphic representing a Topic Exploration Report

August 2026

Status: Incomplete

Chemosaturation for uveal melanoma liver Metastases

Chemosaturation with percutaneous hepatic perfusion of melphalan for liver metastases from uveal melanoma
Read moreabout Chemosaturation for uveal melanoma liver Metastases

July 2026

Status: Complete

Epileptic seizure alarms

Wearable and bed-based technologies to detect tonic-clonic seizures in people with epilepsy
Read moreabout Epileptic seizure alarms
A graphic representing a Topic Exploration Report, Evidence Appraisal and Guidance

July 2026

Status: Complete

Rapid antigen detecting tests

Rapid antigen detection tests for group A streptococcal infections to treat people with a sore throat in the community pharmacy…
Read moreabout Rapid antigen detecting tests